The succinate receptor as a novel therapeutic target for oxidative and metabolic stress-related conditions.
The succinate receptor (also known as GPR91) is a G protein-coupled receptor that is closely related to the family of P2Y purinoreceptors.It is expressed in Shelf a variety of tissues, including blood cells, adipose tissue, the liver, retina and kidney.In these tissues, this receptor and its ligand succinate have recently emerged as novel mediators